Highlights

  • Secrets of metamorphosis

    Interactions between different G-protein signalling pathways ensure that metamorphosis begins in a timely manner in the chordate Ciona.

    Akiko Hozumi, Nozomu M Totsuka ... Yasunori Sasakura
    Research Article
  • Tapeworm larvae and epilepsy

    Amino acids released by larvae of the tapeworm Taenia solium disrupt glutamatergic signalling, which could explain the epileptic seizures caused by these parasites.

    Anja de Lange, Hayley Tomes ... Joseph V Raimondo
    Research Article
  • Exploring VNC neurons

    A library of genetic driver lines makes it possible to manipulate specific neuronal hemilineages in flies.

    Jelly HM Soffers, Erin Beck ... Haluk Lacin
    Research Article

Latest research

    1. Developmental Biology

    Loss of dihydroceramide desaturase drives neurodegeneration by disrupting endoplasmic reticulum and lipid droplet homeostasis in glial cells

    Yuqing Zhu, Kevin Cho ... James B Skeath
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    • Compelling
    1. Evolutionary Biology

    Iridescent structural coloration in a crested Cretaceous enantiornithine bird from Jehol Biota

    Zhiheng Li, Jinsheng Hu ... Julia A Clarke
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Correlates of protection against African swine fever virus identified by a systems immunology approach

    Kirill Lotonin, Francisco Brito ... Artur Summerfield
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Modulation of aperiodic EEG activity provides sensitive index of cognitive state changes during working memory task

    Tisa Frelih, Andraž Matkovič ... Grega Repovš
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology

    Phenylhydrazone-based Endoplasmic Reticulum Proteostasis Regulator Compounds with Enhanced Biological Activity

    Gabriel M Kline, Lisa Boinon ... R Luke Wiseman
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    The influence of temporal context on vision over multiple time scales

    Kacie Lee, Reuben Rideaux
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation

    scRNA+TCR-seq Reveals the Proportion and Characteristics of Dual TCR Treg Cells in Mouse Lymphoid and Non-lymphoid Tissues

    Yuanyuan Xu, Qi Peng ... Xinsheng Yao
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Cell Biology
    2. Immunology and Inflammation

    G1 and G2 ApolipoproteinL1 modulate macrophage inflammation and lipid accumulation through the polyamine pathway

    Esther Liu, Matthew Wright ... Jennie Lin
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Cellular and circuit features distinguish dentate gyrus semilunar granule cells and granule cells activated during contextual memory formation

    Laura Dovek, Mahboubeh Ahmadi ... Vijayalakshmi Santhakumar
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Cell Biology
    2. Genetics and Genomics

    Impact of Maximal Overexpression of a Non-toxic Protein on Yeast Cell Physiology

    Yuri Fujita, Shotaro Namba ... Hisao Moriya
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing